Merck Cements Lead in Lung Cancer With Bristol-Myers Fizzling

Treatment combo nearly doubles survival time in lung cancer patients study finds

Treatment combo nearly doubles survival time in lung cancer patients study finds

Drug treatments from Bristol-Myers Squibb (BMY) and Merck (MRK) created to battle lung cancer both topped expectations in lung cancer, the companies said Monday, but Bristol shares plunged after Merck's combination proved to be stronger. While Bristol-Myers's drug combination also met its goal in certain set of patients, the company still doesn't have overall survival data and doctors may not see enough benefit yet to adopt a regimen that would require additional patient screening.

Both firms tested drugs that harness a patient's immune system to fight cancer.

Cumbre de Lima sería final de las cumbres de las Américas — Maduro
La democracia se ha derrumbado y la dictadura ha crecido. "Tienen una crisis humanitaria brutal", apuntó Nicolás Maduro . La mayoría de los mandatarios de la región manifestaron su preocupación por el uso de armas químicas.

Merck's data showed the efficacy of KEYTRUDA + chemo regardless of PD-1 status TMB burden. Last week, Merck said Keytruda had succeeded in another study as a stand-alone treatment for some lung-cancer patients. Instead of a measure Bristol-Myers had used in past trials, it made a decision to target patients whose tumors have high levels of mutations, known as tumor mutation burden, or TMB. Those results aren't ready yet, though Bristol-Myers said in a statement that "based on an early descriptive analysis, encouraging overall survival was observed with the combination". "All this study does is tell you that TMB is clearly one marker of many that now needs to be considered as we figure out how to use immunotherapy for lung cancer and tumors".

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